Macrophage innate immune responses delineate between defective translocon assemblies produced by Yersinia pseudotuberculosis YopD mutants
ABSTRACTTranslocon pores formed in the eukaryotic cell membrane by a type III secretion system facilitate the translocation of immune-modulatory effector proteins into the host cell interior.The YopB and YopD proteins produced and secreted by pathogenic Yersinia spp.harboring a virulence plasmid-encoded type III secretion system perform this pore-f